Ramipril and Hydrochlorothiazide 5mg/12.5mg

Description

What is HYDRAM 5/12.5?
HYDRAM 5/12.5 contains Ramipril (an ACE inhibitor) and Hydrochlorothiazide (a Thiazide Diuretic).
It is a prescription medication used to treat high blood pressure, and also reduces the risk of heart attack and stroke.
It may also be given to treat heart failure in people who’ve had a heart attack.
Detailed information related to HYDRAM 5/12.5 Tablets’s uses, side-effects, reviews, questions, interactions, and precautions is as follows:

HYDRAM 5/12.5 Uses
HYDRAM 5/12.5 Tablets is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:

• Hypertension
• Congestive Heart Failure (CHF)
• Heart Attack
• Strokes
• Kidney Problems

HYDRAM 5/12.5 Working, Mechanism of Action and Pharmacology
HYDRAM 5/12.5 improves the patient’s condition by performing the following functions:
Ramipril-Angiotensin Converting Enzyme (ACE) inhibitor:

• Ramipril competitively inhibits the conversion of angiotensin I to angiotensin II (a potent endogenous vasoconstrictor) and the bradykinin metabolism; these actions results in dilation of the blood vessels.
• It also inhibits angiotensin-II induced aldosterone secretion, which promotes sodium and water excretion.

Hydrochlorothiazide-Thiazide Diuretics:

• It reduces blood volume by acting on the distal convoluted tubule part of the kidneys to reduce sodium (Na+) reabsorption.
• By impairing Na+ transport, Hydrochlorothiazide induces a natriuresis and concomitant water loss.
• Additionally, in the long run, HCTZ is believed to lower peripheral vascular resistance. These mechanisms result in decreased blood volume, and in turn, reduces the cardiac output, which lowers the Blood Pressure.

HYDRAM 5/12.5 Composition and active ingredients:
Each film coated SEFAM PL 5/10 Tablets is having various prescription medications as given below:

• Ramipril USP 5mg
• Hydrochlorothiazide USP 12.5mg
• Colour: Titanium Dioxide

HYDRAM 5/12.5 – Side-effects
The following is a list of possible side-effects that may occur in medicines that contain HYDRAM 5/12.5. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.

• Dizziness or Faintness
• Cough
• Chest pain
• Edema
• Arrhythmia and Palpitations

HYDRAM 5/12.5 – Precautions & How to Use
Use as directed by your doctor or follow the instructions printed on the product insert.
Consult a doctor, if the condition persists or worsens.
Important counseling points are listed below:

• To prevent dehydration, have plenty of fluids unless the doctor directs you otherwise.
• In patients with diabetes, this product may affect your blood sugar. It is advisable to check your blood sugar regularly as directed and share the results with the doctor. Your doctor may adjust your diabetes medication, exercise program, or diet.
• This product may affect potassium levels. Consult a doctor or pharmacist first before using potassium supplements.
• Do not drive, use heavy machinery, or do anything that needs alertness until it can be done safely.
• Do not use during Lactation and Pregnancy. Consult a doctor first.

Note:
Keep away from the sight and reach of the children.