Perindopril Arginine and Amlodipine Tablets 10mg/5mg

  • Product Name : Perindopril Arginine and Amlodipine Tablets 10mg/5mg
  • Trade Name : SEFAM PL 10/5
  • Available Strength : 5mg/5mg, 5mg/10mg, 10mg/5mg, 10mg/10mg
  • Available Combination : Telmisartan+Amlodipine,Losartan+Amlodipine,Atenolol+Amlodipine,Valsartan+Hydrochlorothiazide+Amlodipine
  • Packing : 3 x 10 Tablets
  • Pack Insert/Leaflet : Yes
  • Therapeutic use : Antihypertensive
  • Production Capacity : 10 million tablet/month
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Description

What is SEFAM PL 10/5?
SEFAM PL 10/5 contains Perindopril Arginine(an ACE inhibitor) and Amlodipine(a calcium channel blocker).
It is a substitution therapy for the treatment of high blood pressure and/or stable coronary heart disease in patients already controlled with separate doses of perindopril and amlodipine.
Treatment should not be initiated with this combination.
Detailed information related to SEFAM PL 10/5 Tablets’s uses, side-effects, reviews, questions, interactions, and precautions is as follows:

SEFAM PL 10/5 Uses
SEFAM PL 10/5 Tablets is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:

  • Hypertension
  • Stable Coronary Artery Disease (CAD)
  • Congestive Heart Failure (CHF)
  • Heart Attack
  • Strokes
  • Kidney Problems

SEFAM PL 10/5 Working, Mechanism of Action and Pharmacology
SEFAM PL 10/5 improves the patient’s condition by performing the following functions:
Perindopril Arginine-angiotensin converting enzyme(ACE) inhibitor:

  • Perindopril Arginine competitively inhibits the conversion of angiotensin I to angiotensin II (a potent endogenous vasoconstrictor) and the bradykinin metabolism; these actions cause dilation of the blood vessels.
  • It also inhibits the secretion of aldosterone induced by angiotensin II, which promotes the excretion of sodium and water.

Amlodipine-calcium channel blocker (CCB):

  • Amlodipine prevents calcium from entering certain tissues and arteries, causing them to relax.
  • As a result, blood can flow more easily to your heart, which in turn helps lower blood pressure.

SEFAM PL 10/5 Composition and active ingredients:
Each film coated SEFAM PL 10/5 Tablets is having various prescription medications as given below:

  • Perindopril Arginine 10mg
  • Amlodipine Besylate USP
  • Equivalent to Amlodipine 5mg
  • Colour: Red Iron Oxide, Yellow Iron Oxide, and Titanium Dioxide

SEFAM PL 10/5 – Side-effects
The following is a list of possible side-effects that may occur in medicines that contain SEFAM PL 10/5. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.

  • Cough
  • Dizziness and Headache
  • Back and chest pain
  • Abnormal ECG
  • Edema
  • Tinnitus
  • Rash, Itching, Eczema
  • Erectile dysfunction

SEFAM PL 10/5 – Precautions & How to Use
Use as directed by your doctor or follow the instructions printed on the product insert.
Consult a doctor, if the condition persists or worsens.
Important counseling points are listed below:

  • To prevent dehydration, have plenty of fluids unless the doctor directs you otherwise.
  • This product may affect potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult a doctor or pharmacist.
  • Do not drive, use heavy machinery, or do anything that needs alertness until it can be done safely.
  • Do not use during Lactation and Pregnancy. Consult a doctor first.

Note:
Keep out of reach of the children.

Additional Information

The most widely recognized markets for this item incorporate the accompanying nations. If you don’t mind ask with us if your nation or district isn’t recorded:

ASIA: Afghanistan, Israel, Jordan, Pakistan, Russia, Saudi Arabia, Singapore, Syria, Philippines, Turkey, Turkmenistan, Uzbekistan, Yemen, Vietnam, Indonesia, Malaysia, Iran, Tajikistan, and so forth.

AFRICA: South Africa, Uganda, Nigeria, Ghana, Kenya, Mauritius, Botswana, Egypt, Ethiopia, Libya, Sudan, Congo, Gambia, Ivory Coast , and so forth.

NORTH & SOUTH AMERICA: USA, Canada, Panama, Trinidad and Tobago, Costa Rica, Puerto Rico, Dominican Republic, Argentina, Guatemala, Guyana, Peru, Bolivia, Venezuela , Brazil, Bahamas, Ecuador, and so forth .

EUROPE: Austria , Azerbaijan, Belarus, Belgium, Cyprus, Czech Republic, Denmark, France, Georgia, Germany, Hungary, Ireland, Iceland, Netherlands, Norway, Poland, Spain, Sweden, Switzerland, Ukraine, United Kingdom (UK) , Latvia, and so forth.

OCEANIA: Australia, New Zealand, Fiji, and so forth.