Amlodipine, Valsartan and Hydrochlorothiazide Tablets USP 10mg/160mg/12.5mg

Description

What is Amzval?
Amzval Tablet contains Amlodipine(a calcium channel blocker), Valsartan(an angiotensin receptor blocker), and Hydrochlorothiazide(a diuretic).
Amzval is a prescription medication used to treat high blood pressure.
Detailed information related to Amzval Tablets’s uses, composition, dosage, side effects and reviews is listed below.

Amzval Uses
Amzval is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:

• Hypertension
• Heart Attack
• Strokes
• Kidney Problems

Amzval Working, Mechanism of Action and Pharmacology
Amzval improves the patient’s condition by performing the following functions:

Amlodipine-calcium channel blocker(CCB):
Amlodipine blocks calcium from entering certain tissues and arteries, which leads to their relaxation.
As a result, blood can flow more easily to your heart, which in turn helps lower the blood pressure.
Taurine improves insulin sensitivity and helps in the conversion of carbohydrates into energy, therefore, it acts as an energy booster.
Amino Acids are important for the absorption of vitamins and minerals & are building blocks of the body thus help in stimulating proper growth and development. Amino Acids such as L-Phenylalanine and L-Tryptophan activate cycle which helps the production of energy in the form of ATP.

Valsartan-Angiotensin II Receptor Blockers(ARBs):
Valsartan works by blocking the effect of angiotensin. This leads to the relaxation of Blood vessels.It also influences the kidney to get rid of extra water and salt. These all, in turn, lead to lowered blood pressure.

Hydrochlorothiazide-Thiazide Diuretics:
It reduces blood volume by acting on the distal convoluted tubule part of the kidneys to reduce sodium (Na+) reabsorption.
By impairing Na+ transport, hydrochlorothiazide induces a natriuresis and concomitant water loss.
Additionally, in the long run, HCTZ is believed to lower peripheral vascular resistance. These mechanisms results in decreased blood volume, and in turn, reduces the cardiac output,which lowers the Blood Pressure

Amzval – Composition and Active Ingredients
Amzval is composed of the following active ingredients (salts)

• Amlodipine Besylate USP
• Equivalent to Amlodipine 10mg
• Valsartan USP 160mg
• Hydrochlorothiazide USP 12.5mg
• Colour: Yellow Iron Oxide and Titanium Dioxide

Please note that this medicine may be available in various strengths for each active ingredient listed above.

Amzval – Precautions & How to Use
Use as directed by your doctor or follow the instructions printed on the product insert.

• To prevent dehydration, have plenty of fluids unless the doctor directs you otherwise.
• In patients with diabetes, this product may affect your blood sugar. It is advisable to check your blood sugar regularly as directed and share the results with the doctor. Your doctor may adjust your diabetes medication, exercise program, or diet.
• This product may affect potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult a doctor or pharmacist.
• Do not drive, use heavy machinery, or do anything that needs alertness until you can do it safely.
• Limit alcoholic beverages.
• Do not use in Pregnancy,Consult a doctor first.

Amzval – Side-effects
The following is a list of possible side-effects that may occur in medicines that contain Amzval. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.

• Eye pain and Decrease in vision
• Dizziness and Headache
• swelling (edema) of the hands, ankles, or feet
• Muscle spasms
• Back pain

Note:
Keep out of reach of the children.