Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin analog (or more specifically, an analog of prostaglandin F2α) that works by increasing the outflow of aqueous fluid from the eyes.
|Appearance||Clear colorless to light yellow oily liquid||Conforms|
|Solubility||Very souble in acetonitrile and ethanol, practically insoluble in water||Conforms|
|Identification||TLC: appear as black spots
HPLC: the retention time of the major peak in the chromatogram of assay preparation corresponds to that of the standard preparation as obtained in the assay.
|Optical rotation||+52.0°~+58.0° (anhydrous and solvent free basis)||+53.6°|
|Residual solvents||Ethyl acetate: NMT 0.5%||ND|
|Related substances||USP travoprost related compound A RS: NMT 0.2%
Epoxide derivative : NMT 0.4%
15-epi Diastereomer: NMT 0.1%
5,6-trans Isomer: NMT 3.5%
15-Keto derivative: NMT 0.3%
Any other individual impurity: NMT 0.1%
Total impurities: NMT 4.0%
|Assay||96.0%~102.0% (anhydrous and solvent free basis)||98.9%|
|Conclusion||Conform to Enterprise standard.|
|Packaging details:||25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.|
|Storage:||Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat|
|Shelf Life:||5 years if sealed and store away from direct sun light.|
The most widely recognized markets for this item incorporate the accompanying nations. If you don’t mind ask with us if your nation or district isn’t recorded:
ASIA: Afghanistan, Israel, Jordan, Pakistan, Russia, Saudi Arabia, Singapore, Syria, Philippines, Turkey, Turkmenistan, Uzbekistan, Yemen, Vietnam, Indonesia, Malaysia, Iran, Tajikistan, and so forth.
AFRICA: South Africa, Uganda, Nigeria, Ghana, Kenya, Mauritius, Botswana, Egypt, Ethiopia, Libya, Sudan, Congo, Gambia, Ivory Coast , and so forth.
NORTH & SOUTH AMERICA: USA, Canada, Panama, Trinidad and Tobago, Costa Rica, Puerto Rico, Dominican Republic, Argentina, Guatemala, Guyana, Peru, Bolivia, Venezuela , Brazil, Bahamas, Ecuador, and so forth .
EUROPE: Austria , Azerbaijan, Belarus, Belgium, Cyprus, Czech Republic, Denmark, France, Georgia, Germany, Hungary, Ireland, Iceland, Netherlands, Norway, Poland, Spain, Sweden, Switzerland, Ukraine, United Kingdom (UK) , Latvia, and so forth.
OCEANIA: Australia, New Zealand, Fiji, and so forth.