Product Category

Propranolol

  • Product Name : Propranolol
  • Grade : IP / BP / USP
  • Therapeutic Category : Antianginal
  • CAS No : 318-98-9
  • COA : Available
  • MSDS : Available
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Description

Description

Propranolol is a medication of the beta blocker type.It is used to treat high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors.It is used to prevent migraine headaches, and to prevent further heart problems in those with angina or previous heart attacks. It can be taken by mouth or by injection into a vein.

 

Specification:

 

Items Specifications Results
Appearance A white or almost white powder Conforms
Solubility Soluble in water and in ethanol (96%) Conforms
Identification
A Melting point : 163°C~166°C 164.0~164.5°C
B Examine by infrared absorption spectrophotometry, comparing with the spectrum obtained with propranolol hydrochloride CRS. Conforms
C Examine by thin-layer chromatography. The principal spot in the chromatogram obtained with the test solution is similar in position, colour and size to the principal spot in the chromatogram obtained with the reference solution. Conforms
D It gives reaction(a) of chlorides Conforms
Tests
Appearance of solution The solution is clear and not more intensely coloured than intensity 6 of the range of reference solutions of the most appropriate colour Conforms
Acidity or alkalinity Add 0.1ml of methyl red solution R and 0.2 ml of 0.01M hydrochloric acid, the solution is red. Add 0.4ml of 0.01 M sodium hydroxide. The solution is yellow. Conforms
Related substances Any impurity NMT 0.1% 0.03%
The sum of all impurities NMT 0.4% 0.21%
Heavy metals NMT 20ppm Conforms
Loss on drying NMT 0.5% 0.11%
Sulphated ash NMT 0.1% 0.08%
Residual solvents A: ethanol: NMT 5000ppm

B: Xylene: NMT 2170ppm

Conforms

Conforms

Assay 99.0%~101.0% 99.3%

 

Packaging details:

 

Packaging details: 25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.
Storage: Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat
Shelf Life: 5 years if sealed and store away from direct sun light.

Additional Information

The most widely recognized markets for this item incorporate the accompanying nations. If you don’t mind ask with us if your nation or district isn’t recorded:

ASIA: Afghanistan, Israel, Jordan, Pakistan, Russia, Saudi Arabia, Singapore, Syria, Philippines, Turkey, Turkmenistan, Uzbekistan, Yemen, Vietnam, Indonesia, Malaysia, Iran, Tajikistan, and so forth.

AFRICA: South Africa, Uganda, Nigeria, Ghana, Kenya, Mauritius, Botswana, Egypt, Ethiopia, Libya, Sudan, Congo, Gambia, Ivory Coast , and so forth.

NORTH & SOUTH AMERICA: USA, Canada, Panama, Trinidad and Tobago, Costa Rica, Puerto Rico, Dominican Republic, Argentina, Guatemala, Guyana, Peru, Bolivia, Venezuela , Brazil, Bahamas, Ecuador, and so forth .

EUROPE: Austria , Azerbaijan, Belarus, Belgium, Cyprus, Czech Republic, Denmark, France, Georgia, Germany, Hungary, Ireland, Iceland, Netherlands, Norway, Poland, Spain, Sweden, Switzerland, Ukraine, United Kingdom (UK) , Latvia, and so forth.

OCEANIA: Australia, New Zealand, Fiji, and so forth.